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Definition of Oxymetholone

Tablets for oral administration each contain 50 mg of the steroid oxymetholone, a potent anabolic and androgenic drug.

Chemical name for oxymetholone, 17β-hydroxy-2-(hydroxymethylene)-17-methyl-5α-androstan-3-one.

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Warnings for Anadrol
Following conditions, reported in patients receiving androgenic anabolic steroids as a general class of drugs:

Peliosis hepatis, a condition in which liver and sometimes splenic tissue replaced with blood-filled cysts, reported in patients receiving androgenic anabolic steroid therapy. Said cysts, sometimes present with minimal hepatic dysfunction, but at other times  associated with liver failure. Often not recognized until life-threatening liver failure or intra-abdominal hemorrhage develops. Withdrawal of drug usually results in complete disappearance of lesions.

Liver cell tumors, also reported. Most often these tumors, benign and androgen-dependent, but fatal malignant tumors reported. Withdrawal of drug often results in regression or cessation of progression of tumors. However, hepatic tumors associated with androgens or anabolic steroids, much more vascular than other hepatic tumors and silent until life-threatening intra-abdominal hemorrhage develops.

Blood lipid changes associated with increased risk of atherosclerosis seen in patients treated with androgens and anabolic steroids. These changes include decreased high density lipoprotein and sometimes increased low density lipoprotein. Changes, very marked  serious impact risk of atherosclerosis and coronary artery disease.

Other Side Effects

Cholestatic hepatitis and jaundice occur with 17-alpha-alkylated androgens at relatively low doses. Clinical jaundice, painless, with or without pruritus. Also associated with acute hepatic enlargement and right upper-quadrant pain. Sometimes mistaken for acute (surgical) obstruction of the bile duct. Drug-induced jaundice usually reversible when the medication discontinued. Continued therapy  associated with hepatic coma and death. Because of the hepatoxicity associated with oxymetholone administration, periodic liver function tests highly recommended.

In patients with breast cancer, anabolic steroid therapy may cause hypercalcemia by stimulating osteolysis. In this case, the drug, discontinued use.

Edema with or without congestive heart failure, a serious complication in patients with pre-existing cardiac, renal or hepatic disease. Concomitant administration with adrenal steroids or ACTH may add to the edema. Generally controllable with appropriate diuretic and/or digitalis therapy.

Geriatric male patients treated with androgenic anabolic steroids, an increased risk for the development of prostate hypertrophy and prostatic carcinoma.

Anabolic steroids have not been shown to enhance athletic ability.

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